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Steven P Treon Selected Research

Waldenstrom Macroglobulinemia (Macroglobulinemia)

1/2022Venetoclax in Previously Treated Waldenström Macroglobulinemia.
1/2022Response and survival predictors in a cohort of 319 patients with Waldenström macroglobulinemia treated with ibrutinib monotherapy.
1/2022Long-term follow-up of ibrutinib monotherapy in treatment-naive patients with Waldenstrom macroglobulinemia.
1/2022Ibrutinib Plus Rituximab Versus Placebo Plus Rituximab for Waldenström's Macroglobulinemia: Final Analysis From the Randomized Phase III iNNOVATE Study.
1/2022Zanubrutinib for the treatment of adults with Waldenstrom macroglobulinemia.
1/2022Natural history of Waldenström macroglobulinemia following acquired resistance to ibrutinib monotherapy.
1/2022SOHO State of the Art Updates and Next Questions: Targeted therapies and emerging novel treatment approaches for Waldenström Macroglobulinemia.
11/2021The HCK/BTK inhibitor KIN-8194 is active in MYD88-driven lymphomas and overcomes mutated BTKCys481 ibrutinib resistance.
11/2021IgM-MM is predominantly a pre-germinal center disorder and has a distinct genomic and transcriptomic signature from WM.
11/2021Single-Agent Ibrutinib for Rituximab-Refractory Waldenström Macroglobulinemia: Final Analysis of the Substudy of the Phase III InnovateTM Trial.
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Steven P Treon Research Topics

Disease

137Waldenstrom Macroglobulinemia (Macroglobulinemia)
01/2022 - 04/2003
48Neoplasms (Cancer)
11/2021 - 06/2002
34Multiple Myeloma
12/2022 - 01/2002
28Lymphoma (Lymphomas)
01/2022 - 04/2003
13Lymphoproliferative Disorders (Lymphoproliferative Disorder)
12/2019 - 04/2003
12Paraproteinemias (Monoclonal Gammopathy)
11/2019 - 04/2003
11B-Cell Lymphoma (Lymphoma, B Cell)
01/2021 - 05/2008
9Disease Progression
01/2020 - 12/2008
8Anemia
11/2019 - 04/2003
8Peripheral Nervous System Diseases (PNS Diseases)
01/2017 - 04/2003
7Non-Hodgkin Lymphoma (Lymphosarcoma)
12/2022 - 03/2005
7Cryoglobulinemia
08/2015 - 04/2003
6Bone Marrow Diseases (Bone Marrow Disease)
10/2021 - 08/2009
6Amyloidosis
11/2016 - 04/2003
6Lymphadenopathy
08/2015 - 04/2003
5Monoclonal Gammopathy of Undetermined Significance
12/2022 - 04/2003
5Autoimmune Hemolytic Anemia (Cold Agglutinin Disease)
11/2021 - 01/2009
5Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)
11/2021 - 02/2011
4Hematologic Neoplasms (Hematological Malignancy)
01/2022 - 12/2006
4Hemorrhage
06/2021 - 11/2006
4Thrombocytopenia (Thrombopenia)
11/2016 - 03/2010
4B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
01/2016 - 04/2003
4Neutropenia
04/2015 - 03/2010
4Cytopenia
08/2014 - 06/2008
4Splenomegaly
03/2010 - 04/2003
3Cardiac Arrhythmias (Arrythmia)
06/2021 - 04/2015
3Atrial Fibrillation
06/2018 - 04/2015
2Infections
05/2022 - 01/2021
2Pneumocystis Pneumonia (Pneumocystis carinii Pneumonia)
01/2019 - 07/2006
2Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular)
01/2016 - 01/2016
2Agammaglobulinemia (Hypogammaglobulinemia)
03/2010 - 06/2008
2Fever (Fevers)
03/2009 - 04/2003
2Leukemia
03/2009 - 01/2009
2type 2C Congenital disorder of glycosylation
12/2008 - 05/2006
2Immunoglobulin Light-chain Amyloidosis
09/2008 - 01/2004
1Respiratory Insufficiency (Respiratory Failure)
05/2022
1COVID-19
05/2022

Drug/Important Bio-Agent (IBA)

60Immunoglobulin M (IgM)IBA
12/2022 - 04/2003
39ibrutinibIBA
05/2022 - 08/2012
25Rituximab (Mabthera)FDA Link
01/2022 - 04/2003
15Bortezomib (Velcade)FDA Link
12/2018 - 10/2002
12Proteins (Proteins, Gene)FDA Link
01/2020 - 04/2003
11Dexamethasone (Maxidex)FDA LinkGeneric
05/2022 - 03/2002
10Agammaglobulinaemia Tyrosine KinaseIBA
01/2022 - 08/2012
10Monoclonal AntibodiesIBA
06/2021 - 04/2003
9Immunoglobulins (Immunoglobulin)IBA
01/2021 - 01/2007
8Immunoglobulin G (IgG)IBA
11/2016 - 12/2005
8Thalidomide (Thalomid)FDA Link
09/2009 - 06/2002
7Proteasome InhibitorsIBA
06/2021 - 06/2002
7Biological ProductsIBA
01/2019 - 01/2002
6ParaproteinsIBA
01/2022 - 08/2005
6Hemoglobins (Hemoglobin)IBA
10/2021 - 04/2003
5Proteasome Endopeptidase Complex (Proteasome)IBA
01/2020 - 10/2002
5AntigensIBA
01/2016 - 04/2003
5Immunoglobulin A (IgA)IBA
07/2014 - 03/2005
5NucleosidesIBA
09/2009 - 04/2003
5NF-kappa B (NF-kB)IBA
05/2008 - 06/2002
4Retinaldehyde (Retinal)IBA
01/2017 - 11/2006
4Alemtuzumab (Campath)FDA Link
07/2011 - 05/2006
3venetoclaxIBA
01/2022 - 07/2015
3Interleukin-6 (Interleukin 6)IBA
01/2018 - 08/2002
3EverolimusFDA Link
05/2017 - 03/2010
3idelalisibIBA
01/2017 - 07/2015
3Cyclophosphamide (Cytoxan)FDA LinkGeneric
06/2015 - 03/2005
3Doxorubicin (Adriamycin)FDA LinkGeneric
04/2012 - 03/2005
3Lenalidomide (CC 5013)FDA Link
01/2009 - 12/2005
3Prednisone (Sone)FDA LinkGeneric
09/2008 - 01/2004
2Histone Deacetylases (Histone Deacetylase)IBA
01/2021 - 09/2011
2CytokinesIBA
01/2021 - 07/2010
2Transcription Factors (Transcription Factor)IBA
01/2020 - 06/2002
2ixazomibIBA
01/2020 - 01/2018
2ResveratrolIBA
08/2019 - 03/2008
26-bromo-2-naphthyl sulfate (BNS)IBA
01/2019 - 03/2016
2MicroRNAs (MicroRNA)IBA
01/2018 - 04/2013
2HepcidinsIBA
04/2013 - 02/2011
2Blood Proteins (Serum Proteins)IBA
04/2013 - 04/2003
2IronIBA
04/2013 - 02/2011
2EnzymesIBA
04/2012 - 03/2011
2VorinostatFDA Link
09/2011 - 04/2003
2Histone Deacetylase InhibitorsIBA
02/2011 - 04/2003
2Vincristine (Oncovin)FDA LinkGeneric
03/2009 - 03/2005
2Hyaluronan SynthasesIBA
12/2008 - 03/2005
2Melphalan (Alkeran)FDA LinkGeneric
09/2008 - 01/2004
2Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
08/2007 - 04/2003
2LigandsIBA
08/2007 - 03/2002
2dacetuzumabIBA
12/2005 - 04/2004
2Alkylating AgentsIBA
03/2005 - 04/2003
2Heat-Shock Proteins (Heat-Shock Protein)IBA
04/2003 - 10/2002
2Insulin-Like Growth Factor I (IGF-1)IBA
10/2002 - 08/2002
1Oxygen (Dioxygen)IBA
05/2022
1remdesivirIBA
05/2022
1A 419259IBA
01/2022
1zanubrutinibIBA
01/2022

Therapy/Procedure

49Therapeutics
05/2022 - 04/2003
5Stem Cell Transplantation
12/2022 - 08/2007
5Drug Therapy (Chemotherapy)
06/2021 - 03/2002
4Plasmapheresis
11/2016 - 03/2008
4Salvage Therapy
01/2013 - 01/2009
3Immunotherapy
01/2017 - 05/2004
3Autologous Transplantation
08/2014 - 03/2005